Andrew Ramos
Andrew attained his Bachelor of Science in Bioengineering at Syracuse University and completed his DPhil in Medical Sciences, under the supervision of Professor Tatjana Sauka-Spengler and Dr Yale Michaels.
He has previously worked on wide range of projects, including those in bone and skin tissue engineering. As a Digital Innovations Project Officer at The Hill, an accelerator based at the John Radcliffe Hospital, he contributed to research assessing the ‘digital health’ ecosystem within Oxfordshire whilst developing a course to introduce clinicians to innovations within healthcare, including machine learning and novel remote monitoring technologies.
Teaching
He has conducted tutorials in genomics based techniques, such as DNA- and RNA-sequencing, and tools to perturb the genome, including RNAi and CRIPR/Cas9.
Research Interests
My research interests lie within synthetic biology, gene therapy, and cancer immunotherapy. My current work investigates chimeric antigen receptor T cells (CAR-T cells). In particular, I use synthetic tools and genomics approaches (e.g. single cell RNA sequencing) to understand and model how CAR expression levels impact the T-cell response and transcriptome - and CAR therapy.
Publications
- Ramos, A, Simon, S., Rajan, A., Siller, J.S., Revale, S., Pelea, O., Fulga, T., Dushek, O., Riddel, S., Michaels, Y† and Sauka-Spengler, T†. CAR expression levels determine T cell transcriptional identity and function. In submission. †denotes equal contribution
- Reidy, C., A’Court, C., Jenkins, W., Jani, A., Ramos, A., Morys-Carter, M., Papoutsi, C. ‘The plural of silo is not ecosystem’: qualitative study on the role of innovation ecosystems in supporting ‘Internet of Things’ applications in health and care. Digital Health 9 (2022)
- Sawyer, S., Dong, P., Venn, S., Ramos, A., Quinn, D., Horton, J., Soman, P. Conductive gelatin methacrylate-poly(aniline) hydrogel for cell encapsulation. Biomedical Physics & Engineering Express 4, 015005 (2018).
- Suvarnapathaki, S., Ramos, R., Sawyer, S., McLoughlin, S., Ramos, A., Venn, S., Soman, P. Generation of cell-laden hydrogel microspheres using 3D printing-enabled microfluidics. Journal of Materials Research 33, 2012-2018 (2018).
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